Hanson Vertical Diffusion Cells & Test Systems

Los Angeles, CA, September 24, 2009—Hanson Research Corp., a world leader in dissolution test technology, also provides an expanded selection of vertical diffusion cells and related equipment for release-rate testing of topical and transdermal formula- tions (see USP Proposed Chapters <3> Topical and Transdermal Drug Products—Product Quality Tests and <725> Topical and Transdermal Drug Products�Product Performance Tests [USP Pharmaco peial Forum, 35/3, May�June 2009]). The Hanson vertical diffusion cell is a simple, reliable, and reproducible means of measuring drug release from semi-solid dosage forms, such as creams, ointments, and gels, and a selection of cell configurations are available. Hanson also provides complete test systems, from manual-sampling techniques to fully automated sampling and collection. Please consult Hanson or visit our Web site at hansonresearch.com for more information.

About Hanson
Hanson Research is a world leader in dissolution test technology for the pharmaceutical industry. Founded in California in 1951, we design, manufacture, install, and service equipment for pharmaceutical research and quality control. We offer a complete line of tablet dissolution, topical, and transdermal test systems and premiered our Vision® dissolution testers in March 2008. We support customers throughout the United States and over 75 countries worldwide.

Contact
Amie C. Martin
Hanson Research Corporation
T. 818.882.7266 x225
F. 818.280.0831
amartin@hansonresearch.com
hansonresearch.com

Press Release

FOR IMMEDIATE RELEASE:

North Brunswick, NJ � September 17, 2009 — Distek has partnered with an outside leasing company to form a private-label financial services group, Distek Financial Services, to offer Distek customers capital and operating leases.

Gerry Brinker, President/Owner of Distek, says, "Forming a financial services arm of Distek will provide our customers with an alternative to an outright purchase at a time when our customers are facing budget freezes or difficulty accessing capital. Financing an equipment purchase allows our customers to acquire the equipment they need now while conserving capital for the future."

CONTACT:
Jeff Seely
Distek, Inc.
888-234-7835 phone
732-422-7310 fax
jeff.seely@distekinc.com
www.distekinc.com

Distek, Inc. is a manufacturer of pharmaceutical laboratory testing equipment, specializing in dissolution products and services. Distek provides solutions for UV Fiber Optics, Media Preparation, Physical Testing, Disintegration, and Validation Services.

Contact: Dr. John Burmicz Sales Director PHARMA TEST Apparatebau AG    j.burmicz@pharma-test.de

PHARMA TEST Apparatebau AG    Siemensstr. 5 63512 Hainburg Germany www.pharma-test.com (phone) (06182) 9532-600 (fax) (06182) 9532-650

The PTWS 100: Compact Dissolution Tester with User-Definable Footprint

The new PTWS 100 from Pharma Test Germany is a compact design Dissolution Tester with a variable footprint that will fit into labs with restricted bench space. PTWS 100 is designed in compliance with the valid USP <711/724> and EP <2.9.3/4> pharmacopeias.

The PTWS 100 represents a true leap forward in dissolution tester technology in practical terms because it offers so much from a relatively compact design.

Configuration: The PTWS 100 can be configured in either a 2 x 3 or 3 x 2 configuration if bench space is limited. The control keypad for system setup and test start is adaptable to be viewed from whichever side is facing the operator.

Staggered Start: As each of the stirrer shafts comes through the control head, the chucks, which ultimately keep the tool at the correct height and allow the drive to be engaged, allow the tool to be dropped into the working position in a staggered-start manner.

Vessel Position: The vessels are held in a self-centering bath in such a way as to always be centered when inserted correctly. They are also maintained in position to comply with current ASTM requirements for vessel wall and tool�vessel conformity with a <1° tolerance for verticality.

Water Bath: The water bath is an economic, injection- molded (blown) acrylic bath that is fully supported and automatically centered upon installation. The heating is maintained by an external, high quality circulator, which may also be placed on the workbench or on the floor below if bench space is restricted.

Touch-Screen Operation: The LCD screen provides the user interface for the instrument. The LCD screen is glass-covered with touch-sensitive areas and navigation buttons to guide the user effortlessly through the setup and running procedures. In keeping with our long-established traffic-light scheme, the screen is backlit with green, amber, or red lighting to indicate the status of the instrument's setup.

Vessel Covers: The vessel covers are also a new design. To maintain the integrity of the vessel position, the vessel covers have a "bayonet"-type locking mechanism. They form part of the vessel cover, which is completed by a Plexiglas (Perspex) disc that is integral to the tool shaft, so vessels, once in position, will always be covered once the tools are lowered. All vessel covers for the PTWS 100 are numerically coded.

System Security: You can preserve the security of the system by allowing user access via password and by taking advantage of the method-management system.

The PTWS 100: At a glance. . .

• Bench space saving design allows for 2 x 3 or 3 x 2 configuration
• Centrally located, electronically controlled lift drive to raise and lower the head
• Touch-screen interface with visual bath-status information and variable display colors
• User-password access and method-management functionality, if required
• PQ interval warning and "wake up" functionality
• Screen-saver function during test runs with display of critical information
• One-piece molded water bath
• Bath cover with automatic vessel-centering feature
• Staggered start for all tool positions
• Monoshaft™ tool design for each tool position
• Individually coded shafts, tools, and covers
• Individual speed control for each stirrer position (optional)
• Interfaces for LAN, USB, or RS232 (optional)

SOTAX Corporation Massachusetts Operations 68 Elm Street, Suite A Hopkinton, MA 01748-1668    USA

Phone (215) 442-1500    1 888 302-9925 Fax (215) 442-1514

sotaxusa@sotax.com www.sotax.com

SOTAX introduces a new Sinker Retrieval Option for the Zymark® MultiDose G3 Workstation

SOTAX has announced a modification to the existing sinker-retrieval platform for the MultiDose G3 Fully Automated Dissolution System, both to increase the reliability of the system and to expand the range of compatible sinker types.

Even though the Zymark® MultiDose G3 can currently accommodate a wide variety of sinker types, a choice that is growing in popularity is the Japanese or "JP" sinker (also described in EP chapter 2.9.3). To utilize this and other larger and heavier sinker types, SOTAX developed a more powerful, rare-earth, capture magnet that is capable of carrying a heavy load at greater operating speeds.

To accommodate the JP sinker and other larger sinker types, the sinker capture module was modified to increase the capture chute and sinker sensor mouth to prevent obstruction. Because of the hardware design changes, it was also possible to increase the speed and efficiency of the sinker retrieval robot.

Altogether, these new modifications showed a failure rate of less than 1�2% in robustness testing and will allow users to run up to 8 batches of fully automated 6-vessel dissolution runs with JP sinkers.

SOTAX is pleased to apply its expertise in fully automated dissolution to the improvement of the MultiDose G3 platform and is committed to serving the MultiDose G3 user community. To obtain more information or to learn how SOTAX can automate your dissolution testing, contact us at sales@sotax.com or visit us at www.sotax.com

Dissolution Solutions Network Undergoes Changes for Web 2.0

Today's internet is rampant with blogs. A blog (a contraction of the term "weblog") is a type of website with regular entries of news, updates, commentary, or other material such as job tips or links. They are followed closely because of the natural drive that people have to communicate. They're becoming more and more popular for three main reasons. They're topical, which means they save time, they allow active interaction, and they provide connection, which is so needed in this high-tech society.

Ten years ago, Peter Scott, a chemist, posted his dissolution notes on the internet for his own reference. As it grew in popularity, he started adding news, stories, links, and updates. This collection, with contributions and help from additional members, became what is now known as the Dissolution Solutions Network (DSN). DSN is now one of the best-known pharmaceutical lab blogs on the web, with information on dissolution testing, HPLC analysis, and other related topics. In its early days, the internet was like a New York subway. It brought you to your destination with little to no human interaction. Today's web, often referred to as Web 2.0, is both an informational and interactive destination, as seen with the popularity of LinkedIn, Facebook, Twitter, and YouTube.

Blogs offer space for readers to comment, disagree, collaborate, and just stay in touch. DSN has undergone a design change to maximize these functionalities. As a result, its recent visitor counts have skyrocketed. DSN allows users to link their entries with a single click to LinkedIn, Twitter, Facebook, e-mail, or other such reposting techniques. Twitter feeds related to the pharmaceutical industry are automatically monitored and reposted on DSN's ever-changing conversation feed. Other leading pharmaceutical news sources, such as the FDA, are reposted electronically to DSN via syndicated news feeds. Visit DSN, www.dissolutionsolutions.net, add comments to stories, add links, find the latest news, and find community.